Scientists & doctors have made tremendous advances in moving regenerative medicine into the mainstream as a treatment for many diseases và disorders. Regenerative medicine takes advantage of our natural ability to heal ourselves by using the healthy adult stem cells found throughout the body. Laboratory and clinical research has shown that it is possible to use adult stem cells to restore lost, damaged or aging cells khổng lồ effectively regenerate tissue & provide some patients with an alternative lớn surgery. Regenerative therapies are showing promise in orthopedic medicine, wound care, nerve restoration, and a variety of cardiovascular, neuromuscular, và autoimmune conditions.
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Stem Cell Therapy
What are Adult Stem Cells?
Adult stem cells were discovered over 40 years ago when researchers found that cells derived from bone marrow had the ability to form various tissues. Adult stem cells are early stage cells that, under the right conditions, are capable of developing into other types of cells và hold the potential to lớn regenerate damaged tissue.AUTOLOGOUS ADULT STEM CELLS (ASCS) are being used to lớn treat many types of chronic pain & degeneration. Currently doctors are treating shoulder, knee, hip, & spine degeneration, in addition to lớn soft tissue (muscle, tendon, ligament) và other bone related injuries.
Who is a Good Candidate for a Stem Cell Procedure?
The first step is to lớn determine if you are a good candidate for an adult stem cell procedure. Your physician will want a history of your injury and a physical examination along with any x-rays, & an MRI. While stem cell therapy maybe appropriate for certain conditions, it is not applicable for every condition. However, it is has proven to lớn be a viable option for several individuals suffering from pain. Good candidates for adult stem cell treatment usually are:
A patient that wants to lớn avoid the inherent complications that come with an invasive surgical procedure A pain sufferer that is interested in an option that offers potential for an overall improved chất lượng of life A person who understands that surgery sets off a cascade of further degeneration, and is prepared to benefit from the body’s own regenerative mechanisms.Every patient is different, the success of the stem cell therapy is dependent on the severity of your condition and your body’s response to lớn stem cell therapy.
Overview of the Procedure
An adult stem cell procedure harnesses’ và amplifies the body’s natural mechanism for healing và anti-inflammation. Once you have been identified as a good candidate for the procedure, a member of our team will reviews the procedure with you and answer any questions that you may have. A brief overview of the procedure is below:
This mechanism uses adult autologous stem cells, derived from your own bone marrow. In the procedure, the physician will aspirate these cells from your hip, concentrate them, then deliver them back into your body toàn thân in the area of damage or injury lớn aid in natural healing. In all, the process takes less than 45 minutes & the concentration of the cells takes about 12-14 minutes. Because your procedure will utilize a concentrated serum of your own cells, the procedure is considered “autologous point-of-care”.Once the procedure is complete, our staff will allow you to rest and will create a customized personal rehabilitation program for recovery. We will either ask you to lớn come back for a few post-operative appointments or follow up with you by phone, email, or mail so we can track you healing progress.
Potential Applications
The spine is comprised of a team environment working together lớn provide function và mobility lớn the body. If an area of the neck or back is injured, the entire structure begins to compensate for the injury causing stability and function to lớn decline. Creating the need to relieve this pain: Possible conditions for treatment are: discogenic back pain, facet arthritis & degenerative disc disease. Your shoulder is involved in small & large movements throughout the day. Shoulder injuries can be the result of the tiniest movements from writing lớn driving a car. Most people do not even know they are suffering from a shoulder injury. Once the injury is identified the pain can become intolerable. Creating the need khổng lồ relieve this pain: Possible conditions for shoulder treatments are partial rotator cuff tears, labral tears, và mild to moderate osteoarthritis The knee joint is used in almost all motion & over time will begin lớn degenerate from overuse. Knee pain can be extremely pain full & challenging for anyone suffering from joint pain. Creating the need to relieve this pain: Possible conditions for knee treatment are osteoarthritis, partial ligament tears: ACL và PCL, partial meniscal tears, & augmented ACL or PCL reconstruction Foot & ankle injuries often occur. Over time, we collect scars making it difficult for our body toàn thân to heal on its own. The constant pressures we cause with simples, line walking or stretching, often exasperate the injury. Creating the need to lớn relieve this pain: Possible conditions for treatment: are mild khổng lồ moderate osteoarthritis, tendon inflammation, partial achilles tendon tear, và muscle strain/sprain.The constant motion of walking, running, biking or climbing involves our hips. The compression of these movements starts to wear on all our joints over time. In addition, the hip’s have a tendency lớn carry much of the burden on our body’s motions & pain. Creating the need to relieve this pain: Possible conditions for treatments are: osteoarthritis, laberal tears, articular cartilage injuries và conginetal deformities of the hipFrequently Asked Questions (FAQs)
Q: What are adult stem cells?
A: Adult stem cells are unspecialized or undifferentiated cells, capable of two processes: self-renewal & differentiation. They are vital to maintaining tissues in the body such as internal organs, skin, & blood.
Q: What is Regenerative Medicine?
A: Regenerative Medicine is a new and advancing scientific field focused on the repair and regeneration of damaged tissue utilizing stem cells.
Q: What is the difference between adult stem cells and embryonic stem cells?
A: Adult stem cells are found in mature adult tissues including bone marrow & fat, while embryonic stem cells (ESCs) are not found in the adult human body. ESCs are obtained from donated in vitro fertilizations, which raises many ethical concerns. Because ESCs are not autologous, there is a possibility of immune rejection. Adult stem cells bởi vì not raise ethical issues nor pose any risks for immune rejection.
Q: Does Dr. Kaplan use embryonic stem cells in clinical procedures?
A: No, Dr. Kaplan’s approach lớn cell therapy relies only on autologous adult stem cells isolated from the patient during surgery. He does not participate in embryonic stem cell research or use embryonic stem cells in clinical applications.
Q: Are there ethical issues associated with harvesting adult stem cells?
A: No, adult stem cells do not raise ethical questions as they are harvested from the patient’s body.
Q: Are there cancer-causing risks associated with adult stem cell treatments?
A: No. Where embryonic stem cells have been shown to size teratomas (germ cell tumors), there is no data that suggests adult stem cells have the same potential khổng lồ promote the development of tumors.
Q: Where vày adult stem cells come from?
A: In adults, stem cells are present within various tissues and organ systems, the most common being bone marrow and adipose or fat tissues. Other sources include the liver, epidermis, retina, skeletal muscle, intestine, brain, placenta, umbilical cord và dental pulp.
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Q: How does Dr. Kaplan obtain adult stem cells for use in cell treatment?
A: Dr. Kaplan currently has a system that uses adult stem cells from bone marrow & these stem cells are obtained through aspiration during your procedure.
Q: How are adult stem cells used in surgical procedures?
A: Adult stem cells are used to lớn treat patients with damaged tissues due khổng lồ age or deterioration. During a procedure, stem cells are isolated from the patient, concentrated và delivered back to lớn the site of injury to lớn assist in the healing process.
Q: Are there different types of adult stem cells?
A: Yes, there are many types of adult stem cells found in the body, which have variable differentiation potentials. The adult stem cells that aid in the repair of damages tissue are multipotent, mesenchymal stem cells. These are located in bone marrow and adipose (fat) tissue.
Q: Are the harvested adult stem cells expanded in a laboratory setting prior to delivery back khổng lồ the patient?
A: No, Dr. Kaplan does not use in vitro expansion. The cells are harvested, processed in the operating room & delivered back to lớn the patient at point of care.
Q: How vì chưng stem cells know what type of tissue lớn develop into?
A: The differentiation of stem cells is dependent on many factors, including cell signaling và micro-environmental signals. Based on these cues, stem cells are able to develop into healthy tissue needed khổng lồ repair damaged tissue. For example, multipotent stem cells delivered khổng lồ damaged bone will develop into bone cells to aid in tissue repair. The exact mechanism of lineage-specific differentiation is unknown at this point.
Q: Will my body toàn thân reject the stem cells?
A: No, adult stem cells are autologous và non-immunogenic.
Q: Is stem cell therapy safe?
A: Yes, and ask your doctor what clinical studies have been done khổng lồ show that stem cells are safe và effective.
Q: Where are stem cells currently being used?
A: Stem cells are currently being used in both laboratory & clinical settings. Laboratories are using human and animal derived stem cells to lớn conduct in vitro studies as well as in vivo studies with small và large animals. Autologous adult stem cells are currently being used in hospitals & clinics during surgery to lớn aid in the repair of damaged tissues.
Q: How long will the stem cells last?
A: It will depend on your injury, the area that is treated và your response lớn the therapy.
Q: What is the recovery lượt thích after a stem cell procedure?
A: If you have a joint injection, you typically can go back to lớn work. It is advised to lớn limit load bearing activities for at least 2 weeks. If you had disc injections, you should take it easy for a few days. Non-steriodal, anti-inflammatory medications (NSAIDS) should be withheld for 72 hours pre-procedure và one week after the procedure.
Q: What is the difference between autologous và allogeneic cells?
A: Autologous cells are taken from the same patient, typically at point-of-care. Allogeneic cells are taken from another patient and are often manipulated before they are given lớn another patient.
Q: Why use adult stem cell therapy rather than pharmaceuticals or genetic treatments?
A: Adult stem cells are from the body toàn thân and generate natural proteins and therapeutic biochemicals, decrease inflammation, are anti-bacterial, & recruit other cells khổng lồ heal the injured site. Pharmaceutical treatments only provide drugs with minimally effective dosages that may cause unwanted side effects. Over dosage can be dangerously toxic or even carcinogenic. Genetic therapy is still unproven & serious concerns exist about it causing cancer due lớn genetically manipulated cells.
Q: What is the difference between autologous and allogeneic cells?
A: Autologous cells are taken from the same patient, typically at point-of-care. Allogeneic cells are taken from another patient & are often manipulated.
Q: How much will it cost?
A: Most insurance will not cover stem cell procedures. Ask your doctor for payment options